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Results 1 to 25 of 47

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Thiopurine S-methyltransferase pharmacogenetics : autophagy as a mechanism for variant allozyme degradationFANG LI; LIEWEI WANG; BURGESS, Rebecca J et al.Pharmacogenetics and genomics (Print). 2008, Vol 18, Num 12, pp 1083-1094, issn 1744-6872, 12 p.Article

Impact of the Heterozygous TPMT*1/*3C Genotype on Azathioprine-Induced Myelosuppression in Kidney Transplant Recipients in ThailandVANNAPRASAHT, Suda; ANGSUTHUM, Susothorn; AVIHINGSANON, Yingyos et al.Clinical therapeutics. 2009, Vol 31, Num 7, pp 1524-1533, issn 0149-2918, 10 p.Article

Genetic determinants of the thiopurine methyltransferase intermediate activity phenotype in British Asians and CaucasiansMARINAKI, Anthony M; ARENAS, Monica; SANDERSON, Jeremy et al.Pharmacogenetics (London). 2003, Vol 13, Num 2, pp 97-105, issn 0960-314X, 9 p.Article

Adding pharmacogenetics information to drug labels: lessons learnedHAGA, Susanne B; THUMMEL, Kenneth E; BURKE, Wylie et al.Pharmacogenetics and genomics (Print). 2006, Vol 16, Num 12, pp 847-854, issn 1744-6872, 8 p.Article

Genetic analysis of thiopurine methyltransferase polymorphism in the Jordanian populationHAKOOZ, Nancy; ARAFAT, Tawfiq; PAYNE, Debbie et al.European journal of clinical pharmacology. 2010, Vol 66, Num 10, pp 999-1003, issn 0031-6970, 5 p.Article

Thiopurine S-methyltransferase pharmacogenetics: chaperone protein association and allozyme degradationLIEWEI WANG; SULLIVAN, William; TOFT, David et al.Pharmacogenetics (London). 2003, Vol 13, Num 9, pp 555-564, issn 0960-314X, 10 p.Article

Choice of azathioprine or 6-mercaptopurine dose based on thiopurine methyltransferase (TPMT) activity to avoid myelosuppression. A prospective studyGISBERT, Javier P; LUNA, Marta; MATE, José et al.Hepato-gastroenterology. 2006, Vol 53, Num 69, pp 399-404, issn 0172-6390, 6 p.Article

Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel diseaseGEARRY, Richard B; BARCLAY, Murray L.Journal of gastroenterology and hepatology. 2005, Vol 20, Num 8, pp 1149-1157, issn 0815-9319, 9 p.Article

Thiopurine methyltransferase (TPMT) heterozygosity and enzyme activity as predictive tests for the development of azathioprine-related adverse eventsHECKMANN, Jeannine M; LAMBSON, Elisabetta M. T; LITTLE, Francesca et al.Journal of the neurological sciences. 2005, Vol 231, Num 1-2, pp 71-80, issn 0022-510X, 10 p.Article

Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variantsSCHAEFFELER, Elke; FISCHER, Christine; BROCKMEIER, Dierk et al.Pharmacogenetics (London). 2004, Vol 14, Num 7, pp 407-417, issn 0960-314X, 11 p.Article

The Cost-Effectiveness of a Pharmacogenetic Test: A Trial-Based Evaluation of TPMT Genotyping for AzathioprineTHOMPSON, Alexander J; NEWMAN, William G; ELLIOTT, Rachel A et al.Value in health. 2014, Vol 17, Num 1, pp 22-33, issn 1098-3015, 12 p.Article

Pre-analytic and analytic sources of variations in thiopurine methyltransferase activity measurement in patients prescribed thiopurine-based drugs: A systematic reviewLOIT, Evelin; TRICCO, Andrea C; TSOUROS, Sophia et al.Clinical biochemistry. 2011, Vol 44, Num 10-11, pp 751-757, issn 0009-9120, 7 p.Article

Analysis of variation in mouse TPMT genotype, expression and activityWATTERS, James W; WANGHAI ZHANG; MEUCCI, Melissa A et al.Pharmacogenetics (London). 2004, Vol 14, Num 4, pp 247-254, issn 0960-314X, 8 p.Article

Comment prescrire l'azathioprine en pratique clinique? = How to treat patients with azathioprine in clinical practice?ROBLIN, Xavier.La Lettre de l'hépato-gastroentérologue. 2013, Vol 16, Num 1, pp 39-41, issn 1286-580X, 3 p.Article

Limitations of extensive TPMT genotyping in the management of azathioprine-induced myelosuppression in IBD patientsDEWIT, O; MOREELS, T; VAN OUTRYVE, M et al.Clinical biochemistry. 2011, Vol 44, Num 13, pp 1062-1066, issn 0009-9120, 5 p.Article

Paradoxical Elevated Thiopurine S-Methyltransferase Activity After Pancytopenia During Azathioprine Therapy : Potential Influence of Red Blood Cell AgeDE BOER, Nanne K. H; VAN BODEGRAVEN, Adriaan A; DE GRAAF, Peer et al.Therapeutic drug monitoring. 2008, Vol 30, Num 3, pp 390-393, issn 0163-4356, 4 p.Article

Thiopurine S-methyltransferase pharmacogenetics : variant allele functional and comparative genomicsSALAVAGGIONE, Oreste E; LIEWEI WANG; WIEPERT, Mathieu et al.Pharmacogenetics and genomics (Print). 2005, Vol 15, Num 11, pp 801-815, issn 1744-6872, 15 p.Article

Biotransformation of 6-thioguanine in inflammatory bowel disease patients: a comparison of oral and intravenous administration of 6-thioguanineJHARAP, B; DE BOER, Nkh; VOS, R. M et al.British journal of pharmacology. 2011, Vol 163, Num 4, pp 722-731, issn 0007-1188, 10 p.Article

Association between inosine triphosphate pyrophosphohydrolase deficiency and azathioprine-related adverse drug reactions in the Chinese kidney transplant recipientsHUI XIONG; XIN, Hua-Wen; WU, Xiao-Chun et al.Fundamental & clinical pharmacology. 2010, Vol 24, Num 3, pp 393-400, issn 0767-3981, 8 p.Article

TPMT but not ITPA gene polymorphism influences the risk of azathioprine intolerance in renal transplant recipientsKURZAWSKI, Mateusz; DZIEWANOWSKI, Krzysztof; LENER, Agnieszka et al.European journal of clinical pharmacology. 2009, Vol 65, Num 5, pp 533-540, issn 0031-6970, 8 p.Article

Thiopurine methyltransferase activity in Spain : A study of 14,545 patientsGISBERT, Javier P; GOMOLLON, Fernando; CARA, Carlos et al.Digestive diseases and sciences. 2007, Vol 52, Num 5, pp 1262-1269, issn 0163-2116, 8 p.Article

Thiopurine S-methyltransferase genetic polymorphism in the Thai populationSRIMANPIROM, Somrudee; TASSANEEYAKUL, Wongwiwat; KUKONGVIRIYAPAN, Veerapol et al.British journal of clinical pharmacology. 2004, Vol 58, Num 1, pp 66-70, issn 0306-5251, 5 p.Article

Thiopurine methyltransferase phenotypes and genotypes in BraziliansREIS, Marcelo; SANTORO, Ana; SUAREZ-KURTZ, Guilherme et al.Pharmacogenetics (London). 2003, Vol 13, Num 6, pp 371-373, issn 0960-314X, 3 p.Article

Suivi thérapeutique pharmacologique des 6-thioguanine nucléotides dans les leucémies aigues lymphoblastiques de l'enfant: intérêt et limites = Therapeutic Drug Monitoring of 6-Thioguanine Nucleotides in Paediatric Acute Lymphoblastic Leukaemia: Interest and LimitsFAKHOURY, May; DE BEAUMAIS, Tiphaine; MEDARD, Yves et al.Thérapie (Paris). 2010, Vol 65, Num 3, pp 187-193, issn 0040-5957, 7 p.Article

Thiopurine S-methyltransferase pharmacogenetics : insights, challenges and future directionsWANG, L; WEINSHILBOUM, R.Oncogene (Basingstoke). 2006, Vol 25, Num 11, pp 1629-1638, issn 0950-9232, 10 p.Article

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